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BDBM50368570 CHEMBL1794908

SMILES: COC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](O)[C@H](N)CCCCN

InChI Key: InChIKey=CGMUBURMPMVFHE-DJIMGWMZSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50368570   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aminopeptidase N


(Rattus norvegicus)
BDBM50368570
PNG
(CHEMBL1794908)
Show SMILES COC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](O)[C@H](N)CCCCN
Show InChI InChI=1S/C19H28N4O4/c1-27-19(26)16(10-12-11-22-15-8-3-2-6-13(12)15)23-18(25)17(24)14(21)7-4-5-9-20/h2-3,6,8,11,14,16-17,22,24H,4-5,7,9-10,20-21H2,1H3,(H,23,25)/t14-,16-,17-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.26E+5n/an/an/an/an/an/a



Instituto de Qu£mica M£dica

Curated by ChEMBL


Assay Description
Inhibitory potency against purified membrane bound rat brain Aminopeptidase M using [3H]Leu-enkephalin as substrate


J Med Chem 35: 889-95 (1992)


Article DOI: 10.1021/jm00083a013
BindingDB Entry DOI: 10.7270/Q2X92BWN
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50368570
PNG
(CHEMBL1794908)
Show SMILES COC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](O)[C@H](N)CCCCN
Show InChI InChI=1S/C19H28N4O4/c1-27-19(26)16(10-12-11-22-15-8-3-2-6-13(12)15)23-18(25)17(24)14(21)7-4-5-9-20/h2-3,6,8,11,14,16-17,22,24H,4-5,7,9-10,20-21H2,1H3,(H,23,25)/t14-,16-,17-/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



Instituto de Qu£mica M£dica

Curated by ChEMBL


Assay Description
Inhibitory potency against purified membrane bound rat brain Aminopeptidase B using L-lysine-beta napthylamide as substrate


J Med Chem 35: 889-95 (1992)


Article DOI: 10.1021/jm00083a013
BindingDB Entry DOI: 10.7270/Q2X92BWN
More data for this
Ligand-Target Pair