BDBM50368642 ACETYLPEPSTATIN

SMILES CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)C(C)C)[C@@H](O)CC(O)=O

InChI Key InChIKey=WKYBEGDEGRCZNF-LBTYKNIQSA-N

Data  6 KI  3 IC50  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50368642   

TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50368642(ACETYLPEPSTATIN)
Affinity DataKi:  0.0200nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50368642(ACETYLPEPSTATIN)
Affinity DataKi:  5nMAssay Description:The compound was tested for its affinity against HIV -2 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50368642(ACETYLPEPSTATIN)
Affinity DataKi:  20nMAssay Description:Binding affinity against HIV-1 aspartic proteinase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50368642(ACETYLPEPSTATIN)
Affinity DataKi:  20nMAssay Description:Binding affinity for HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50368642(ACETYLPEPSTATIN)
Affinity DataKi:  35nMAssay Description:Binding affinity to HIV-1 proteaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50368642(ACETYLPEPSTATIN)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50368642(ACETYLPEPSTATIN)
Affinity DataKd:  208nMAssay Description:Binding affinity to Human immunodeficiency virus 1 protease by SPR biosensor interaction analysis at pH 4.1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50368642(ACETYLPEPSTATIN)
Affinity DataKd:  8.15E+3nMAssay Description:Binding affinity to Human immunodeficiency virus 1 protease by SPR biosensor interaction analysis at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50368642(ACETYLPEPSTATIN)
Affinity DataKd:  759nMAssay Description:Binding affinity to Human immunodeficiency virus 1 protease by SPR biosensor interaction analysis at pH 5.1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50368642(ACETYLPEPSTATIN)
Affinity DataIC50:  240nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Abz-Ala-Arg-Val-Nle-Tyr(NO2)-Glu-Ala-Nle-NH2 peptide as substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50368642(ACETYLPEPSTATIN)
Affinity DataKd:  19nMAssay Description:Affinity for HIV ProteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50368642(ACETYLPEPSTATIN)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of bovine spleen cathepsin B using Z-Arg-Arg-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50368642(ACETYLPEPSTATIN)
Affinity DataIC50:  232nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed