BDBM50369150 CHEMBL1788226

SMILES CN1CCC[C@@H]1c1cncc(c1)C#C

InChI Key InChIKey=NUPUDYKEEJNZRG-GFCCVEGCSA-N

Data  1 IC50  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50369150   

TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
SIBIA Neurosciences Inc

Curated by PDSP Ki Database
LigandPNGBDBM50369150(CHEMBL1788226)
Affinity DataEC50:  6.80E+4nMAssay Description:The compound was tested on recombinant human alpha4-beta2 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
SIBIA Neurosciences Inc

Curated by PDSP Ki Database
LigandPNGBDBM50369150(CHEMBL1788226)
Affinity DataEC50:  7.00E+3nMAssay Description:The compound was tested on recombinant human alpha4-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit delta(Torpedo californica)
SIBIA Neurosciences Inc

Curated by PDSP Ki Database
LigandPNGBDBM50369150(CHEMBL1788226)
Affinity DataEC50:  6.80E+4nMAssay Description:The compound was tested on recombinant human alpha3-beta4 cell lines of HUman embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit delta(Torpedo californica)
SIBIA Neurosciences Inc

Curated by PDSP Ki Database
LigandPNGBDBM50369150(CHEMBL1788226)
Affinity DataEC50:  3.10E+4nMAssay Description:The compound was tested on recombinant human alpha3-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50369150(CHEMBL1788226)
Affinity DataEC50:  9.00E+3nMAssay Description:Binding affinity at NAChRs was determined by measuring the displacement of ([3H]Nic) from a preparation of rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50369150(CHEMBL1788226)
Affinity DataEC50:  2.90E+4nMAssay Description:Binding affinity at NAChRs was determined by measuring the displacement of ([3H]Nic) from a preparation of rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
SIBIA Neurosciences Inc

Curated by PDSP Ki Database
LigandPNGBDBM50369150(CHEMBL1788226)
Affinity DataIC50:  4.50E+3nMAssay Description:The compound was tested on recombinant human alpha4-beta4 cell lines of HUman embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed