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BDBM50369630 CHEMBL1927724

SMILES: COc1ccc(Cn2c(=O)[nH]c3ccccc3c2=O)cc1

InChI Key: InChIKey=FPSKZBZKHJDYAF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50369630   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sphingomyelin phosphodiesterase


(Homo sapiens)
BDBM50369630
PNG
(CHEMBL1927724)
Show SMILES COc1ccc(Cn2c(=O)[nH]c3ccccc3c2=O)cc1
Show InChI InChI=1S/C16H14N2O3/c1-21-12-8-6-11(7-9-12)10-18-15(19)13-4-2-3-5-14(13)17-16(18)20/h2-9H,10H2,1H3,(H,17,20)
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.50E+5n/an/an/an/an/an/a



Furtwangen University

Curated by ChEMBL


Assay Description
Inhibition of mmLDL-stimulated acid sphingomyelinase in human PBMC lysates using 3H-sphingomyelin as substrate preincubated for 30 mins followed by m...


Eur J Med Chem 153: 73-104 (2018)


Article DOI: 10.1016/j.ejmech.2017.09.021
BindingDB Entry DOI: 10.7270/Q2B85BPG
More data for this
Ligand-Target Pair