BDBM50370452 CHEMBL132589::FR-181157

SMILES [O-]C(=O)COc1cccc(C[C@@H]2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1

InChI Key InChIKey=QVZSFHJAGXKMMQ-DEOSSOPVSA-M

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50370452   

TargetProstacyclin receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50370452(CHEMBL132589 | FR-181157)
Affinity DataKi:  54nMAssay Description:Displacement of [3H]iloprost from human Prostanoid IP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50370452(CHEMBL132589 | FR-181157)
Affinity DataKi:  54nMAssay Description:Ability to inhibit binding of [3H]iloprost to cloned human prostaglandin I2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50370452(CHEMBL132589 | FR-181157)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]PGD-2 from human Prostanoid DP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50370452(CHEMBL132589 | FR-181157)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]PGF-2 from human Prostanoid FP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50370452(CHEMBL132589 | FR-181157)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]PGE-2 from human Prostanoid EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50370452(CHEMBL132589 | FR-181157)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-PGE-2 from human Prostanoid EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50370452(CHEMBL132589 | FR-181157)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]SQ-29,548 from human Prostanoid TP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50370452(CHEMBL132589 | FR-181157)
Affinity DataKi:  1.02E+3nMAssay Description:Displacement of [3H]PGE-2 from human Prostanoid EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50370452(CHEMBL132589 | FR-181157)
Affinity DataKi:  6.80E+3nMAssay Description:Displacement of [3H]PGE-2 from human Prostanoid EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed