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BDBM50370558 CHEMBL609376

SMILES: OC[C@H]1OC([C@H](O)[C@@H]1O)n1c(nc2c(SCc3ccccc3)ncnc12)N1CCCC1

InChI Key: InChIKey=DUACVZOIDOBZNS-UZFSNFJHNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50370558   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Equilibrative Nucleoside Transporter 1 (ENT1)


(Homo sapiens (Human))
BDBM50370558
PNG
(CHEMBL609376)
Show SMILES OC[C@H]1OC([C@H](O)[C@@H]1O)n1c(nc2c(SCc3ccccc3)ncnc12)N1CCCC1
Show InChI InChI=1/C21H25N5O4S/c27-10-14-16(28)17(29)20(30-14)26-18-15(24-21(26)25-8-4-5-9-25)19(23-12-22-18)31-11-13-6-2-1-3-7-13/h1-3,6-7,12,14,16-17,20,27-29H,4-5,8-11H2/t14-,16-,17-,20?/s2
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Similars

Article
PubMed
410n/an/an/an/an/an/an/an/a



Leiden University

Curated by ChEMBL


Assay Description
Inhibition of [3H]NBTI binding to equilibrative nucleoside transport protein 1 (ENT1) in human erythrocyte membranes


J Med Chem 48: 321-9 (2005)


Article DOI: 10.1021/jm049303k
BindingDB Entry DOI: 10.7270/Q29024J0
More data for this
Ligand-Target Pair