BDBM50370925 CHEMBL1627233
SMILES C[C@H](CC=S(N)(=O)c1ccccc1)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C
InChI Key InChIKey=IXLSAZXSMBBARI-IQUVVAJASA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50370925
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University
Curated by ChEMBL
Cardiff University
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University
Curated by ChEMBL
Cardiff University
Curated by ChEMBL
Affinity DataIC50: 7.40nMAssay Description:Inhibition of human CYP24 hydroxylase expressed in V79 cellsMore data for this Ligand-Target Pair
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University
Curated by ChEMBL
Cardiff University
Curated by ChEMBL
Affinity DataIC50: 7.40nMAssay Description:Inhibition of human CYP24A1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University
Curated by ChEMBL
Cardiff University
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of human CYP24 hydroxylase expressed in V79 cellsMore data for this Ligand-Target Pair
TargetSterol 26-hydroxylase, mitochondrial(Homo sapiens (Human))
The Johns Hopkins University
Curated by ChEMBL
The Johns Hopkins University
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human CYP27A1 hydroxylase expressed in V79 cellsMore data for this Ligand-Target Pair
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Homo sapiens (Human))
The Johns Hopkins University
Curated by ChEMBL
The Johns Hopkins University
Curated by ChEMBL
Affinity DataIC50: 554nMAssay Description:Inhibition of human CYP27B hydroxylase expressed in SW900 cellsMore data for this Ligand-Target Pair