BDBM50372142 CHEMBL271441

SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2cncc3[nH]nc(N)c23)c1

InChI Key InChIKey=BDPBZUHWAVABDM-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50372142   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50372142(CHEMBL271441)
Affinity DataIC50:  1nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50372142(CHEMBL271441)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of KDR by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50372142(CHEMBL271441)
Affinity DataIC50:  1nMAssay Description:Inhibition of KDR (unknown origin) in cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50372142(CHEMBL271441)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of KDR kinase activity (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50372142(CHEMBL271441)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of KDR kinase activity (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50372142(CHEMBL271441)
Affinity DataIC50:  1nMAssay Description:Inhibition of KDR (unknown origin) in cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article