BDBM50372197 CHEMBL258083

SMILES CCC[C@H]1CCN[C@H](C1)[C@@H](O)[C@H](Cc1cc(F)cc(F)c1)NC(=O)c1cc(C)cc(c1)C(=O)N(CCC)CCC

InChI Key InChIKey=MMSXGVAPNNIHSW-GEYQZXRLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50372197   

TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372197(CHEMBL258083)
Affinity DataIC50:  70nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372197(CHEMBL258083)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human BACE1 assessed as amyloid beta 40 production in human HEK293 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed