BDBM50373071 CHEMBL255489

SMILES: CN(CCN(C)Cc1coc2cc(C)c(C)cc2c1=O)Cc1cn(-c2cccc(c2)C(F)(F)F)c2ccccc12

InChI Key: InChIKey=JZNXLPPJRFFECJ-UHFFFAOYSA-N

Data: 7 IC50  16 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50373071   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tumor necrosis factor (Human)	BDBM50373071 (CHEMBL255489) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5.36E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tumor necrosis factor (Human)	BDBM50373071 (CHEMBL255489) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tumor necrosis factor (Human)	BDBM50373071 (CHEMBL255489) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tumor necrosis factor (Human)	BDBM50373071 (CHEMBL255489) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tumor necrosis factor receptor superfamily member 1A (Human)	BDBM50373071 (CHEMBL255489) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tumor necrosis factor (Human)	BDBM50373071 (CHEMBL255489) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.81	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tumor necrosis factor (Human)	BDBM50373071 (CHEMBL255489) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5.36E+3	n/a	n/a	n/a	6.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tumor necrosis factor (Human)	BDBM50373071 (CHEMBL255489) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tumor necrosis factor (Human)	BDBM50373071 (CHEMBL255489) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	7.34E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tumor necrosis factor (Human)	BDBM50373071 (CHEMBL255489) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	7.51E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tumor necrosis factor (Human)	BDBM50373071 (CHEMBL255489) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5.75E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tumor necrosis factor (Human)	BDBM50373071 (CHEMBL255489) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	8.44E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tumor necrosis factor (Human)	BDBM50373071 (CHEMBL255489) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tumor necrosis factor (Human)	BDBM50373071 (CHEMBL255489) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6.18E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tumor necrosis factor (Human)	BDBM50373071 (CHEMBL255489) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tumor necrosis factor (Human)	BDBM50373071 (CHEMBL255489) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	9.77E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tumor necrosis factor (Human)	BDBM50373071 (CHEMBL255489) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.18E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tumor necrosis factor (Human)	BDBM50373071 (CHEMBL255489) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tumor necrosis factor (Human)	BDBM50373071 (CHEMBL255489) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11 (Human)	BDBM50373071 (CHEMBL255489) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.38E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11 (Human)	BDBM50373071 (CHEMBL255489) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tumor necrosis factor (Human)	BDBM50373071 (CHEMBL255489) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	9.17E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11 (Human)	BDBM50373071 (CHEMBL255489) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.38E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair