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BDBM50373359 CHEMBL258746

SMILES: CN1CCN(CC1)c1cc2[nH]c(SCc3ccc(F)cc3)nc2cc1F

InChI Key: InChIKey=NPSUGZFKWNMBHA-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50373359   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nociceptin receptor


(Homo sapiens (Human))
BDBM50373359
PNG
(CHEMBL258746)
Show SMILES CN1CCN(CC1)c1cc2[nH]c(SCc3ccc(F)cc3)nc2cc1F
Show InChI InChI=1S/C19H20F2N4S/c1-24-6-8-25(9-7-24)18-11-17-16(10-15(18)21)22-19(23-17)26-12-13-2-4-14(20)5-3-13/h2-5,10-11H,6-9,12H2,1H3,(H,22,23)
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Similars

Article
PubMed
n/an/a 910n/an/an/an/an/an/a



Banyu Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Displacement of [125I]Tyr14-NC from human ORL1 receptor expressed in CHO cell membrane


Bioorg Med Chem Lett 18: 3278-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.054
BindingDB Entry DOI: 10.7270/Q2HT2Q57
More data for this
Ligand-Target Pair