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BDBM50373524 CHEMBL403924

SMILES: CC(C)[C@H](NC(=O)CCN(C)C)c1cccc(F)c1N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1cccc(Cl)c1)C(C)C

InChI Key: InChIKey=PPTOSGVZGIFRJG-QXIHQKPUSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50373524   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50373524
PNG
(CHEMBL403924)
Show SMILES CC(C)[C@H](NC(=O)CCN(C)C)c1cccc(F)c1N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1cccc(Cl)c1)C(C)C
Show InChI InChI=1S/C33H47ClFN5O2/c1-22(2)31(36-30(41)13-14-37(5)6)26-11-8-12-29(35)32(26)38-15-17-39(18-16-38)33(42)28-21-40(23(3)4)20-27(28)24-9-7-10-25(34)19-24/h7-12,19,22-23,27-28,31H,13-18,20-21H2,1-6H3,(H,36,41)/t27-,28+,31-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
370n/an/an/an/an/an/an/an/a



Neurocrine Biosciences Inc

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human MC4 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 18: 129-36 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.115
BindingDB Entry DOI: 10.7270/Q2MK6DR5
More data for this
Ligand-Target Pair