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BDBM50374112 CHEMBL258302

SMILES: C(Cc1ccc(cc1)C1=CCC2CN(CC12)c1cncnc1)N1CCCC1

InChI Key: InChIKey=GDPOVVOCCNPUOW-UHFFFAOYNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50374112   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50374112
PNG
(CHEMBL258302)
Show SMILES C(Cc1ccc(cc1)C1=CCC2CN(CC12)c1cncnc1)N1CCCC1
Show InChI InChI=1/C23H28N4/c1-2-11-26(10-1)12-9-18-3-5-19(6-4-18)22-8-7-20-15-27(16-23(20)22)21-13-24-17-25-14-21/h3-6,8,13-14,17,20,23H,1-2,7,9-12,15-16H2
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UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
7n/an/an/an/an/an/an/an/a



Arena Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex


Bioorg Med Chem Lett 18: 1490-4 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.059
BindingDB Entry DOI: 10.7270/Q2Q81DZS
More data for this
Ligand-Target Pair