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BDBM50374989 CHEMBL412302

SMILES: NCCCn1cc(C2=C(C(=O)NC2=O)c2cccc(Br)c2)c2ccccc12

InChI Key: InChIKey=ZEZMHMCYCHJAFT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50374989   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Calcium/calmodulin-dependent protein kinase type II subunit delta


(Homo sapiens (Human))
BDBM50374989
PNG
(CHEMBL412302)
Show SMILES NCCCn1cc(C2=C(C(=O)NC2=O)c2cccc(Br)c2)c2ccccc12
Show InChI InChI=1S/C21H18BrN3O2/c22-14-6-3-5-13(11-14)18-19(21(27)24-20(18)26)16-12-25(10-4-9-23)17-8-2-1-7-15(16)17/h1-3,5-8,11-12H,4,9-10,23H2,(H,24,26,27)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 180n/an/an/an/an/an/a



Scios Inc

Curated by ChEMBL


Assay Description
Inhibition of CaMK2delta


Bioorg Med Chem Lett 18: 2395-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.058
BindingDB Entry DOI: 10.7270/Q2QZ2BVW
More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit delta


(Homo sapiens (Human))
BDBM50374989
PNG
(CHEMBL412302)
Show SMILES NCCCn1cc(C2=C(C(=O)NC2=O)c2cccc(Br)c2)c2ccccc12
Show InChI InChI=1S/C21H18BrN3O2/c22-14-6-3-5-13(11-14)18-19(21(27)24-20(18)26)16-12-25(10-4-9-23)17-8-2-1-7-15(16)17/h1-3,5-8,11-12H,4,9-10,23H2,(H,24,26,27)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 180n/an/an/an/an/an/a



Scios Inc

Curated by ChEMBL


Assay Description
Inhibition of CaMK2delta


Bioorg Med Chem Lett 18: 2390-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.059
BindingDB Entry DOI: 10.7270/Q27W6D2W
More data for this
Ligand-Target Pair