BDBM50375736 CHEMBL404837

SMILES Nc1ccc(cc1C(=O)NCC(=O)N[C@@H]1CCN(Cc2ccc(Cl)cc2)C1)[N+]([O-])=O

InChI Key InChIKey=ARJKTLVBNOCOHR-OAHLLOKOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50375736   

TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Deltagen Research Laboratories (Former Combichem)

Curated by ChEMBL
LigandPNGBDBM50375736(CHEMBL404837)
Affinity DataIC50:  208nMAssay Description:Displacement of [125I]MCP1 from human CCR2b in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Deltagen Research Laboratories (Former Combichem)

Curated by ChEMBL
LigandPNGBDBM50375736(CHEMBL404837)
Affinity DataIC50:  43nMAssay Description:Antagonist activity at human CCR2 in THP1 cells assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed