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BDBM50375838 CHEMBL271835

SMILES: Cn1c(ccc1-c1cc2c(N(Cc3ccccc3)C(=O)C2(C)C)c(F)c1)C#N

InChI Key: InChIKey=FPYZTDDUPXWEQH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50375838   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Progesterone receptor


(Homo sapiens (Human))
BDBM50375838
PNG
(CHEMBL271835)
Show SMILES Cn1c(ccc1-c1cc2c(N(Cc3ccccc3)C(=O)C2(C)C)c(F)c1)C#N
Show InChI InChI=1S/C23H20FN3O/c1-23(2)18-11-16(20-10-9-17(13-25)26(20)3)12-19(24)21(18)27(22(23)28)14-15-7-5-4-6-8-15/h4-12H,14H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 164n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase


J Med Chem 51: 1861-73 (2008)


Article DOI: 10.1021/jm701080t
BindingDB Entry DOI: 10.7270/Q2G44R56
More data for this
Ligand-Target Pair