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BDBM50376100 CHEMBL260678

SMILES: O=C1Cc2c([nH]c3ccccc23)-c2ncccc2N1

InChI Key: InChIKey=GVRZEQYUWSXMPG-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50376100   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (Human))
BDBM50376100
PNG
(CHEMBL260678)
Show SMILES O=C1Cc2c([nH]c3ccccc23)-c2ncccc2N1
Show InChI InChI=1S/C15H11N3O/c19-13-8-10-9-4-1-2-5-11(9)18-14(10)15-12(17-13)6-3-7-16-15/h1-7,18H,8H2,(H,17,19)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9.00E+3n/an/an/an/an/an/a



Technische Universit£t Braunschweig

Curated by ChEMBL


Assay Description
Inhibition of recombinant CDK5/p25 expressed in Escherichia coli


J Med Chem 51: 2196-207 (2008)


Article DOI: 10.1021/jm701582f
BindingDB Entry DOI: 10.7270/Q2SF2X22
More data for this
Ligand-Target Pair