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BDBM50376268 CHEMBL405387

SMILES: CN(CC1CCCCC1)c1ccc(cc1)C(=O)Nc1cnc2ccccc2c1

InChI Key: InChIKey=HJSSFRYDNBPQOI-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50376268   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM50376268
PNG
(CHEMBL405387)
Show SMILES CN(CC1CCCCC1)c1ccc(cc1)C(=O)Nc1cnc2ccccc2c1
Show InChI InChI=1S/C24H27N3O/c1-27(17-18-7-3-2-4-8-18)22-13-11-19(12-14-22)24(28)26-21-15-20-9-5-6-10-23(20)25-16-21/h5-6,9-16,18H,2-4,7-8,17H2,1H3,(H,26,28)
PDB
MMDB

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B.MOAD
DrugBank
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
16n/an/an/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL


Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 18: 2730-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.075
BindingDB Entry DOI: 10.7270/Q27H1KF6
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM50376268
PNG
(CHEMBL405387)
Show SMILES CN(CC1CCCCC1)c1ccc(cc1)C(=O)Nc1cnc2ccccc2c1
Show InChI InChI=1S/C24H27N3O/c1-27(17-18-7-3-2-4-8-18)22-13-11-19(12-14-22)24(28)26-21-15-20-9-5-6-10-23(20)25-16-21/h5-6,9-16,18H,2-4,7-8,17H2,1H3,(H,26,28)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 170n/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL


Assay Description
Activity at human TRPV1 in HEK cells assessed by measuring capsaicin-induced calcium level by FLIPR technology


Bioorg Med Chem Lett 18: 2730-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.075
BindingDB Entry DOI: 10.7270/Q27H1KF6
More data for this
Ligand-Target Pair