BDBM50376358 CHEMBL259013

SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2ccc(cc2)C(F)(F)F)cc1

InChI Key InChIKey=GACBELOLIOXYRT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50376358   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50376358(CHEMBL259013)
Affinity DataIC50:  110nMAssay Description:Inhibition of KDR in presence of 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50376358(CHEMBL259013)
Affinity DataIC50:  2.44E+3nMAssay Description:Inhibition of VEGF-induced KDR phosphorylation in mouse 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50376358(CHEMBL259013)
Affinity DataIC50:  35nMAssay Description:Inhibition of cKitMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50376358(CHEMBL259013)
Affinity DataIC50:  9nMAssay Description:Inhibition of Flt3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed