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BDBM50376443 CHEMBL262867

SMILES: CCNC(=O)c1cn2ncnc(Nc3cc(NC(=O)c4cccc(c4)-n4ccnc4)ccc3C)c2c1C

InChI Key: InChIKey=WYNNXHJPDJLRHD-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50376443   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50376443
PNG
(CHEMBL262867)
Show SMILES CCNC(=O)c1cn2ncnc(Nc3cc(NC(=O)c4cccc(c4)-n4ccnc4)ccc3C)c2c1C
Show InChI InChI=1S/C27H26N8O2/c1-4-29-27(37)22-14-35-24(18(22)3)25(30-15-31-35)33-23-13-20(9-8-17(23)2)32-26(36)19-6-5-7-21(12-19)34-11-10-28-16-34/h5-16H,4H2,1-3H3,(H,29,37)(H,32,36)(H,30,31,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7n/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Inhibition of p38alpha


Bioorg Med Chem Lett 18: 2739-44 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.067
BindingDB Entry DOI: 10.7270/Q29887X6
More data for this
Ligand-Target Pair