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BDBM50376453 CHEMBL442462

SMILES: CCCNC(=O)c1cn2ncnc(Nc3cc(NC(=O)c4cc(F)cc(c4)N4CCOCC4)ccc3C)c2c1C

InChI Key: InChIKey=VHIZLNMGYAFBOD-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50376453   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50376453
PNG
(CHEMBL442462)
Show SMILES CCCNC(=O)c1cn2ncnc(Nc3cc(NC(=O)c4cc(F)cc(c4)N4CCOCC4)ccc3C)c2c1C
Show InChI InChI=1S/C29H32FN7O3/c1-4-7-31-29(39)24-16-37-26(19(24)3)27(32-17-33-37)35-25-15-22(6-5-18(25)2)34-28(38)20-12-21(30)14-23(13-20)36-8-10-40-11-9-36/h5-6,12-17H,4,7-11H2,1-3H3,(H,31,39)(H,34,38)(H,32,33,35)
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MMDB

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PC sid
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Similars

Article
PubMed
n/an/a 5n/an/an/an/an/an/a



Bristol-Myers Squibb

Curated by ChEMBL


Assay Description
Inhibition of p38alpha


Bioorg Med Chem Lett 18: 2739-44 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.067
BindingDB Entry DOI: 10.7270/Q29887X6
More data for this
Ligand-Target Pair