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BDBM50376709 CHEMBL258961

SMILES: Cc1cc(C)c2oc(nc2c1)-c1ccc(NC(=O)COc2ccc(OC(F)(F)F)cc2)cc1

InChI Key: InChIKey=UKHLSOJGHXUXNV-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50376709   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cholesteryl ester transfer protein


(Homo sapiens (Human))
BDBM50376709
PNG
(CHEMBL258961)
Show SMILES Cc1cc(C)c2oc(nc2c1)-c1ccc(NC(=O)COc2ccc(OC(F)(F)F)cc2)cc1
Show InChI InChI=1S/C24H19F3N2O4/c1-14-11-15(2)22-20(12-14)29-23(32-22)16-3-5-17(6-4-16)28-21(30)13-31-18-7-9-19(10-8-18)33-24(25,26)27/h3-12H,13H2,1-2H3,(H,28,30)
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human CETP by scintillation proximity assay


Bioorg Med Chem Lett 18: 2640-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.03.030
BindingDB Entry DOI: 10.7270/Q2V40W3V
More data for this
Ligand-Target Pair