BDBM50376748 CHEMBL259739::Phen-DC3

SMILES C[n+]1cc(NC(=O)c2ccc3ccc4ccc(nc4c3n2)C(=O)Nc2c[n+](C)c3ccccc3c2)cc2ccccc12

InChI Key InChIKey=CTOLNXAGCUTHBW-UHFFFAOYSA-P

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50376748   

TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes Of Health, National Institutes Of Health Biomedical Research Center

LigandPNGBDBM50376748(CHEMBL259739 | Phen-DC3)
Affinity DataIC50:  65nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes Of Health, National Institutes Of Health Biomedical Research Center

LigandPNGBDBM50376748(CHEMBL259739 | Phen-DC3)
Affinity DataIC50:  370nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes Of Health, National Institutes Of Health Biomedical Research Center

LigandPNGBDBM50376748(CHEMBL259739 | Phen-DC3)
Affinity DataIC50:  0.370nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes Of Health, National Institutes Of Health Biomedical Research Center

LigandPNGBDBM50376748(CHEMBL259739 | Phen-DC3)
Affinity DataIC50:  50nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50376748(CHEMBL259739 | Phen-DC3)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated before telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50376748(CHEMBL259739 | Phen-DC3)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated after telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50376748(CHEMBL259739 | Phen-DC3)
Affinity DataIC50:  790nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells in presence of primer (T2AG3)3 by primer extension assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50376748(CHEMBL259739 | Phen-DC3)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells in presence of primer TS by primer extension assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50376748(CHEMBL259739 | Phen-DC3)
Affinity DataIC50:  63nMAssay Description:Inhibition of human telomerase expressed in in HEK293T cells in presence of primer (T2AG3)4 by primer extension assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes Of Health, National Institutes Of Health Biomedical Research Center

LigandPNGBDBM50376748(CHEMBL259739 | Phen-DC3)
Affinity DataIC50:  130nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed