BDBM50376803 CHEMBL262330

SMILES CCc1cccc(CC)c1-c1cc(OC)c2C(CCCc2n1)N1CCc2cccc(c2C1)C(F)(F)F

InChI Key InChIKey=WHPOPVNAZREUII-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50376803   

TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50376803(CHEMBL262330)
Affinity DataKi:  9.70nMAssay Description:Displacement of [125I]C5a from human C5a receptor in U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50376803(CHEMBL262330)
Affinity DataIC50:  270nMAssay Description:Antagonist activity at human C5a receptor in U937 cells assessed as inhibition of anaphylatoxin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed