BDBM50377852 CHEMBL261655

SMILES COc1cccc(CN2C[C@H](NC2=O)C(=O)N[C@@H](Cc2ccccc2)[C@H](O)CNCc2cccc(c2)N(C)C)c1

InChI Key InChIKey=MCBWJRZWLSXSBN-YTCPBCGMSA-N

Data  2 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50377852   

TargetCathepsin D(Homo sapiens (Human))
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50377852(CHEMBL261655)
Affinity DataKi:  195nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50377852(CHEMBL261655)
Affinity DataKi:  449nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50377852(CHEMBL261655)
Affinity DataIC50:  1.42E+4nMAssay Description:Inhibition of human BACE1 by SEAP reporter gene assayMore data for this Ligand-Target Pair