BDBM50331515 CHEMBL1708::PAROXETINE::Paroxetine hydrochloride::Paroxetine.HCl::Paxil::Paxil cr

SMILES: c1cc(ccc1[C@@H]2CCNC[C@H]2COc3ccc4c(c3)OCO4)F

InChI Key: InChIKey=AHOUBRCZNHFOSL-UHFFFAOYSA-N

Data: 4 KI  18 IC50

PDB links: 10 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 50331515   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 3A4 (Human)	BDBM50331515 (PAROXETINE | Paxil | CHEMBL1708 | Paxil cr | Parox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rhodopsin kinase GRK1 (Bovine)	BDBM50331515 (PAROXETINE | Paxil | CHEMBL1708 | Paxil cr | Parox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.16E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G protein-coupled receptor kinase 5 (Bovine)	BDBM50331515 (PAROXETINE | Paxil | CHEMBL1708 | Paxil cr | Parox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.51E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G protein-coupled receptor kinase 5 (Bovine)	BDBM50331515 (PAROXETINE | Paxil | CHEMBL1708 | Paxil cr | Parox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.26E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rhodopsin kinase GRK1 (Bovine)	BDBM50331515 (PAROXETINE | Paxil | CHEMBL1708 | Paxil cr | Parox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.58E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G protein-coupled receptor kinase 5 (Bovine)	BDBM50331515 (PAROXETINE | Paxil | CHEMBL1708 | Paxil cr | Parox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.26E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM50331515 (PAROXETINE | Paxil | CHEMBL1708 | Paxil cr | Parox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rhodopsin kinase GRK1 (Bovine)	BDBM50331515 (PAROXETINE | Paxil | CHEMBL1708 | Paxil cr | Parox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.98E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2C8 (Human)	BDBM50331515 (PAROXETINE | Paxil | CHEMBL1708 | Paxil cr | Parox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Human)	BDBM50331515 (PAROXETINE | Paxil | CHEMBL1708 | Paxil cr | Parox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Human)	BDBM50331515 (PAROXETINE | Paxil | CHEMBL1708 | Paxil cr | Parox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM50331515 (PAROXETINE | Paxil | CHEMBL1708 | Paxil cr | Parox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.89E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Human)	BDBM50331515 (PAROXETINE | Paxil | CHEMBL1708 | Paxil cr | Parox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Human)	BDBM50331515 (PAROXETINE | Paxil | CHEMBL1708 | Paxil cr | Parox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM50331515 (PAROXETINE | Paxil | CHEMBL1708 | Paxil cr | Parox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 4 (Human)	BDBM50331515 (PAROXETINE | Paxil | CHEMBL1708 | Paxil cr | Parox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 3 (Human)	BDBM50331515 (PAROXETINE | Paxil | CHEMBL1708 | Paxil cr | Parox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 2 (Human)	BDBM50331515 (PAROXETINE | Paxil | CHEMBL1708 | Paxil cr | Parox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rat)	BDBM50331515 (PAROXETINE | Paxil | CHEMBL1708 | Paxil cr | Parox...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM50331515 (PAROXETINE | Paxil | CHEMBL1708 | Paxil cr | Parox...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transporter (Rat)	BDBM50331515 (PAROXETINE | Paxil | CHEMBL1708 | Paxil cr | Parox...) Show SMILES Show InChI	GoogleScholar	UniChem		59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM50331515 (PAROXETINE | Paxil | CHEMBL1708 | Paxil cr | Parox...) Show SMILES Show InChI	GoogleScholar	UniChem		98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair