BDBM50378050 CHEMBL557281

SMILES CC(C)C(Oc1cccc2ccccc12)C(=O)Nc1ccc(Cl)cc1

InChI Key InChIKey=QZKIXDSVUHUHBH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50378050   

TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50378050(CHEMBL557281)
Affinity DataIC50:  700nMAssay Description:Inhibition of Cryptosporidium IMPDH preincubated for 10 mins before substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50378050(CHEMBL557281)
Affinity DataIC50:  830nMAssay Description:Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli TX685 assessed as NADH production by fluorescence assay in prese...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50378050(CHEMBL557281)
Affinity DataIC50:  710nMAssay Description:Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli TX685 assessed as NADH production by fluorescence assay in absen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase(Bacillus anthracis)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50378050(CHEMBL557281)
Affinity DataIC50:  120nMAssay Description:Inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed