BDBM50378299 CHEMBL568079

SMILES CC(C)n1cnc2c(NCc3ccc(s3)-c3cccc(F)c3)nc(N[C@H]3CC[C@H](N)CC3)nc12

InChI Key InChIKey=LYESIQXGSHOWNN-WGSAOQKQSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50378299   

TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL

LigandBDBM50378299(CHEMBL568079)Copy SMILESCopy InChI

Affinity DataIC50:  0.25nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri

Curated by ChEMBL

LigandBDBM50378299(CHEMBL568079)Copy SMILESCopy InChI

Affinity DataIC50:  0.0900nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI