BDBM50378739 SINEFUNGIN::jm2c00120, Sinefungin

SMILES: c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@@H]([C@H](O3)C[C@H](CC[C@@H](C(=O)O)N)N)O)O)N

InChI Key: InChIKey=LMXOHSDXUQEUSF-UHFFFAOYSA-N

Data: 2 KI  41 IC50  3 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 46 hits for monomerid = 50378739   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-lysine N-methyltransferase EHMT2 (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	278	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase NSD2 (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	278	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Genome polyprotein (ZIKV)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.92E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
mRNA cap guanine-N7 methyltransferase (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase NSD3 (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase, H3 lysine-36 specific (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase NSD2 (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase NSD2 (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
tRNA (cytosine(38)-C(5))-methyltransferase (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.09E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-arginine methyltransferase CARM1 (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase NSD2 (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 1 (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 1 (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase SETD7 (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.13E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT2 (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.09E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thiopurine S-methyltransferase (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Genome polyprotein (ZIKV)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (SARS-CoV)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT2 (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT2 (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase, H3 lysine-79 specific (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Genome polyprotein (ZIKV)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
mRNA cap guanine-N7 methyltransferase (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
mRNA cap guanine-N7 methyltransferase (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
mRNA cap guanine-N7 methyltransferase (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycine N-methyltransferase (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.16E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
tRNA (cytosine(38)-C(5))-methyltransferase (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
tRNA (cytosine(38)-C(5))-methyltransferase (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indolethylamine N-methyltransferase (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		4.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (Human)	BDBM50378739 (SINEFUNGIN | jm2c00120, Sinefungin) Show SMILES Show InChI	GoogleScholar	UniChem		1.26E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair