BDBM50379143 CHEMBL2012825::US8703811, 38

SMILES O=C(NC1CCC1)c1ccc(s1)-n1cnc2ccccc12

InChI Key InChIKey=WREVZKANZSJFPC-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50379143   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50379143(CHEMBL2012825 | US8703811, 38)Copy SMILESCopy InChI

Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human DHODH after 20 mins by 2,6-dichloroindophenol-reduction based assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
Genzyme

US Patent

LigandBDBM50379143(CHEMBL2012825 | US8703811, 38)Copy SMILESCopy InChI

Affinity DataIC50:  418nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/TrEMBL
B.MOADDrugBankGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI