BindingDB logo
myBDB logout

BDBM50379345 CHEMBL2011921

SMILES: CNc1c(Br)cnc2nc([nH]c12)-c1ccc2n[nH]cc2c1

InChI Key: InChIKey=PWWKDIFQICRXDB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50379345   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase TBK1


(Homo sapiens (Human))
BDBM50379345
PNG
(CHEMBL2011921)
Show SMILES CNc1c(Br)cnc2nc([nH]c12)-c1ccc2n[nH]cc2c1
Show InChI InChI=1S/C14H11BrN6/c1-16-11-9(15)6-17-14-12(11)19-13(20-14)7-2-3-10-8(4-7)5-18-21-10/h2-6H,1H3,(H,18,21)(H2,16,17,19,20)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 288n/an/an/an/an/an/a



AstraZeneca R&D Boston

Curated by ChEMBL


Assay Description
Inhibition of recombinant TBK1 using 5FAM-AhxKRRAL(ps)VASLPGL as substrate by microfluidic mobility shift assay


Bioorg Med Chem Lett 22: 2063-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.01.018
BindingDB Entry DOI: 10.7270/Q2WS8V74
More data for this
Ligand-Target Pair