BDBM50379414 CHEMBL2012028

SMILES Nc1ccnc(Nc2ccc(Oc3ccc(F)cc3)cc2)n1

InChI Key InChIKey=CSMDEJLWCPVNEJ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50379414   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50379414(CHEMBL2012028)
Affinity DataKi:  1.90E+3nMAssay Description:Displacement of dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50379414(CHEMBL2012028)
Affinity DataIC50:  780nMAssay Description:Antagonist activity at human partially inactivated NaV 1.5 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50379414(CHEMBL2012028)
Affinity DataIC50:  1.20E+3nMAssay Description:Antagonist activity at human partially inactivated NaV 1.7 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed