BDBM482157 BDBM50379529::LRRK2-IN-1::US11370796, Compound LRRK2-IN-1

SMILES: CN1CCN(CC1)C2CCN(CC2)C(=O)c3ccc(c(c3)OC)Nc4ncc5c(n4)N(c6ccccc6C(=O)N5C)C

InChI Key: InChIKey=IWMCPJZTADUIFX-UHFFFAOYSA-N

Data: 16 IC50  6 Kd

PDB links: 9 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 482157   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain testis-specific protein (Human)	BDBM482157 (LRRK2-IN-1 | BDBM50379529 | US11370796, Compound L...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Human)	BDBM482157 (LRRK2-IN-1 | BDBM50379529 | US11370796, Compound L...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Human)	BDBM482157 (LRRK2-IN-1 | BDBM50379529 | US11370796, Compound L...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Human)	BDBM482157 (LRRK2-IN-1 | BDBM50379529 | US11370796, Compound L...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Human)	BDBM482157 (LRRK2-IN-1 | BDBM50379529 | US11370796, Compound L...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Human)	BDBM482157 (LRRK2-IN-1 | BDBM50379529 | US11370796, Compound L...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Human)	BDBM482157 (LRRK2-IN-1 | BDBM50379529 | US11370796, Compound L...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Human)	BDBM482157 (LRRK2-IN-1 | BDBM50379529 | US11370796, Compound L...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Human)	BDBM482157 (LRRK2-IN-1 | BDBM50379529 | US11370796, Compound L...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain testis-specific protein (Human)	BDBM482157 (LRRK2-IN-1 | BDBM50379529 | US11370796, Compound L...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain testis-specific protein (Human)	BDBM482157 (LRRK2-IN-1 | BDBM50379529 | US11370796, Compound L...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [1326-2527] (Human)	BDBM482157 (LRRK2-IN-1 | BDBM50379529 | US11370796, Compound L...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM482157 (LRRK2-IN-1 | BDBM50379529 | US11370796, Compound L...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	194	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM482157 (LRRK2-IN-1 | BDBM50379529 | US11370796, Compound L...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM482157 (LRRK2-IN-1 | BDBM50379529 | US11370796, Compound L...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Human)	BDBM482157 (LRRK2-IN-1 | BDBM50379529 | US11370796, Compound L...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Human)	BDBM482157 (LRRK2-IN-1 | BDBM50379529 | US11370796, Compound L...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Human)	BDBM482157 (LRRK2-IN-1 | BDBM50379529 | US11370796, Compound L...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Human)	BDBM482157 (LRRK2-IN-1 | BDBM50379529 | US11370796, Compound L...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [1326-2527,A2016T,G2019S] (Human)	BDBM482157 (LRRK2-IN-1 | BDBM50379529 | US11370796, Compound L...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [1326-2527,A2016T] (Human)	BDBM482157 (LRRK2-IN-1 | BDBM50379529 | US11370796, Compound L...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [1326-2527,G2019S] (Human)	BDBM482157 (LRRK2-IN-1 | BDBM50379529 | US11370796, Compound L...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair