BDBM50379632 CHEMBL2011349

SMILES C1CN(CCN1)c1ccnc(Nc2ncc(s2)-c2cncc(c2)-c2cn[nH]c2)c1

InChI Key InChIKey=BQLMSQOLZAQQCV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50379632   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50379632(CHEMBL2011349)
Affinity DataIC50:  8nMAssay Description:Inhibition of CHK1 by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50379632(CHEMBL2011349)
Affinity DataIC50:  260nMAssay Description:Inhibition of CDK7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50379632(CHEMBL2011349)
Affinity DataIC50:  8nMAssay Description:Competitive inhibition of Chk1 in presence of higher ATP levelsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed