BDBM50380446 CHEMBL2018756

SMILES CCOC(=O)Nc1ccc(Nc2ncnc3cc(OC)c(OC)cc23)cc1C

InChI Key InChIKey=QEKKQKSAUFTIBW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50380446   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50380446(CHEMBL2018756)
Affinity DataIC50:  900nMAssay Description:Inhibition of human EGFR after 1 hr using [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50380446(CHEMBL2018756)
Affinity DataIC50:  650nMAssay Description:Inhibition of recombinant human VEGFR-2 using poly(Glu4/Tyr) and [gamma32P]ATP as substrate after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50380446(CHEMBL2018756)
Affinity DataIC50:  900nMAssay Description:Inhibition of human EGFR expressed in human A431 cells using poly(Glu4/Tyr) and [gamma32P]ATP as substrate after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50380446(CHEMBL2018756)
Affinity DataIC50:  500nMAssay Description:Inhibition of human recombinant VEGFR-2 after 1 hr using [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed