BDBM50380625 CHEMBL2016872
SMILES NC(=N)c1ccc(CNC(=O)[C@@H]2Cc3ccc(OCCCCOc4ccc(C[C@@H](NS(=O)(=O)Cc5ccccc5)C(=O)N2)cc4)cc3)cc1
InChI Key InChIKey=HFYJVMKRIIAVFV-SZAHLOSFSA-N
Data 9 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50380625
Affinity DataKi: 1.10nMAssay Description:Inhibition of plasmin by dixon plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Inhibition of plasma kallikrein by dixon plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 34.2nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
Affinity DataKi: 510nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
Affinity DataKi: 510nMAssay Description:Inhibition of thrombin by dixon plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 784nMAssay Description:Inhibition of factor 10a by dixon plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.01E+3nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Philipps University Marburg
Curated by ChEMBL
Philipps University Marburg
Curated by ChEMBL
Affinity DataKi: 4.59E+3nMAssay Description:Inhibition of activated protein C by dixon plot methodMore data for this Ligand-Target Pair