BDBM50380626 CHEMBL2016874
SMILES NC(=N)c1ccc(CNC(=O)[C@@H]2Cc3cn(Cc4cccc(Cn5cc(C[C@@H](NS(=O)(=O)Cc6ccccc6)C(=O)N2)nn5)n4)nn3)cc1
InChI Key InChIKey=PODBMIDYMFKRKE-URLMMPGGSA-N
Data 9 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50380626
Affinity DataKi: 2.20nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Inhibition of plasmin by dixon plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 10.1nMAssay Description:Inhibition of plasma kallikrein by dixon plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 10.1nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
Affinity DataKi: 1.86E+3nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
Affinity DataKi: 1.86E+3nMAssay Description:Inhibition of factor 10a by dixon plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 4.56E+3nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
Affinity DataKi: 6.18E+3nMAssay Description:Inhibition of thrombin by dixon plot methodMore data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Philipps University Marburg
Curated by ChEMBL
Philipps University Marburg
Curated by ChEMBL
Affinity DataKi: 8.39E+3nMAssay Description:Inhibition of activated protein C by dixon plot methodMore data for this Ligand-Target Pair