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BDBM50380700 CHEMBL2017656

SMILES: CCOP(=O)(OCC)C(Cc1ccc(OC(F)(F)F)cc1)c1sc2ccccc2c1C

InChI Key: InChIKey=BMJFFVYIVRGIMZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50380700   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential M8 protein (TRPM8)


(Canis lupus familiaris (Dog))
BDBM50380700
PNG
(CHEMBL2017656)
Show SMILES CCOP(=O)(OCC)C(Cc1ccc(OC(F)(F)F)cc1)c1sc2ccccc2c1C
Show InChI InChI=1S/C22H24F3O4PS/c1-4-27-30(26,28-5-2)19(21-15(3)18-8-6-7-9-20(18)31-21)14-16-10-12-17(13-11-16)29-22(23,24)25/h6-13,19H,4-5,14H2,1-3H3
KEGG

UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 240n/an/an/an/an/an/a



Janssen Pharmaceutica NV

Curated by ChEMBL


Assay Description
Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...


Bioorg Med Chem Lett 22: 2922-6 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.060
BindingDB Entry DOI: 10.7270/Q2TM7C48
More data for this
Ligand-Target Pair