BDBM50380710 CHEMBL2017667

SMILES: CCOP(=O)(OCC)C(Cc1ccc(F)c(F)c1)c1sc2ccccc2c1CC(C)(C)C

InChI Key: InChIKey=CHBSSVLVGYVFLG-UHFFFAOYSA-N

Data: 1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50380710   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50380710 (CHEMBL2017667) Show SMILES CCOP(=O)(OCC)C(Cc1ccc(F)c(F)c1)c1sc2ccccc2c1CC(C)(C)C Show InChI InChI=1S/C25H31F2O3PS/c1-6-29-31(28,30-7-2)22(15-17-12-13-20(26)21(27)14-17)24-19(16-25(3,4)5)18-10-8-9-11-23(18)32-24/h8-14,22H,6-7,15-16H2,1-5H3	KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV Curated by ChEMBL					Assay Description Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ level measured eve...				Bioorg Med Chem Lett 22: 2922-6 (2012) Article DOI: 10.1016/j.bmcl.2012.02.060 BindingDB Entry DOI: 10.7270/Q2TM7C48
					More data for this Ligand-Target Pair