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BDBM50380902 CHEMBL2016657

SMILES: COc1c(Br)c(Br)c(C(=O)c2c(Br)c(Br)c(OC)c(OC)c2Br)c(Br)c1OC

InChI Key: InChIKey=QMAHLSLYICNNAA-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50380902   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50380902
PNG
(CHEMBL2016657)
Show SMILES COc1c(Br)c(Br)c(C(=O)c2c(Br)c(Br)c(OC)c(OC)c2Br)c(Br)c1OC
Show InChI InChI=1S/C17H12Br6O5/c1-25-14-9(20)5(7(18)11(22)16(14)27-3)13(24)6-8(19)12(23)17(28-4)15(26-2)10(6)21/h1-4H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.02E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged human recombinant PTB1B using pNPP as substrate after 3 mins


Bioorg Med Chem Lett 22: 2827-32 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.074
BindingDB Entry DOI: 10.7270/Q28K7B33
More data for this
Ligand-Target Pair