BDBM50381096 CHEMBL2017556

SMILES CCC(O)(CC)c1ccc2cc([nH]c2c1)-c1n[nH]c2cc(sc12)C(F)F

InChI Key InChIKey=CQZZZUNOWZUNNG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50381096   

TargetTyrosine-protein kinase ITK/TSK(Human)
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381096(CHEMBL2017556)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Itk (357-620) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381096(CHEMBL2017556)
Affinity DataIC50: 39.2nMAssay Description:Inhibition of Lck autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase TXK(Human)
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381096(CHEMBL2017556)
Affinity DataIC50: 77.5nMAssay Description:Inhibition of Txk autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381096(CHEMBL2017556)
Affinity DataIC50: 358nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Syk (343 to 635) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed