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BDBM50381222 CHEMBL2018536

SMILES: CCC[C@H](O)[C@H](CN(C)Cc1ccc(C)cc1C)NC(=O)CNC(=O)c1cc(ccc1NC(=O)NC(C)C)C(F)(F)F

InChI Key: InChIKey=BVWJBXPYCNRVLJ-QYRYXDJWNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50381222   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM50381222
PNG
(CHEMBL2018536)
Show SMILES CCC[C@H](O)[C@H](CN(C)Cc1ccc(C)cc1C)NC(=O)CNC(=O)c1cc(ccc1NC(=O)NC(C)C)C(F)(F)F
Show InChI InChI=1/C30H42F3N5O4/c1-7-8-26(39)25(17-38(6)16-21-10-9-19(4)13-20(21)5)36-27(40)15-34-28(41)23-14-22(30(31,32)33)11-12-24(23)37-29(42)35-18(2)3/h9-14,18,25-26,39H,7-8,15-17H2,1-6H3,(H,34,41)(H,36,40)(H2,35,37,42)/t25-,26-/s2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 440n/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Displacement of [125-I]MCP1 from CCR2 on human PBMC


Bioorg Med Chem Lett 22: 3311-6 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.007
BindingDB Entry DOI: 10.7270/Q2PN96MB
More data for this
Ligand-Target Pair