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BDBM50381632 CHEMBL2023435

SMILES: [#6]\[#6](-[#6])=[#6]\[#6]-[#8]-c1cc(-[#8]-c2ccc(cc2)S(=O)(=O)[#7]-2-[#6]-[#6]-3-[#6]-[#6]-[#6](-[#6]-2)-[#8]-3)cc(c1)-[#6](=O)-[#7]-c1ccn(-[#6])n1

InChI Key: InChIKey=MOGIBPAWZYJFHG-UHFFFAOYNA-N

Data: 1 EC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50381632   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucokinase/Glucokinase regulatory protein


(Homo sapiens (Human))
BDBM50381632
PNG
(CHEMBL2023435)
Show SMILES CC(C)=CCOc1cc(Oc2ccc(cc2)S(=O)(=O)N2CC3CCC(C2)O3)cc(c1)C(=O)Nc1ccn(C)n1
Show InChI InChI=1/C28H32N4O6S/c1-19(2)11-13-36-24-14-20(28(33)29-27-10-12-31(3)30-27)15-25(16-24)37-21-6-8-26(9-7-21)39(34,35)32-17-22-4-5-23(18-32)38-22/h6-12,14-16,22-23H,4-5,13,17-18H2,1-3H3,(H,29,30,33)
PDB
MMDB

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UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 242n/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Activation of human recombinant glucokinase expressed in Escherichia coli BL21(DE3) coexpressing G6PDH assessed as glucose 6-phosphate formation by s...


Bioorg Med Chem 20: 2982-91 (2012)


Article DOI: 10.1016/j.bmc.2012.03.008
BindingDB Entry DOI: 10.7270/Q2H1331F
More data for this
Ligand-Target Pair