BindingDB logo
myBDB logout

BDBM50381804 CHEMBL2023626

SMILES: O=C(Oc1ccc2c(ccnc2c1)-c1cnn(c1)-c1ccccc1)N1CCOCC1

InChI Key: InChIKey=VLQXGUZUMLSXOK-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50381804   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 4 (mGluR4)


(Homo sapiens (Human))
BDBM50381804
PNG
(CHEMBL2023626)
Show SMILES O=C(Oc1ccc2c(ccnc2c1)-c1cnn(c1)-c1ccccc1)N1CCOCC1
Show InChI InChI=1S/C23H20N4O3/c28-23(26-10-12-29-13-11-26)30-19-6-7-21-20(8-9-24-22(21)14-19)17-15-25-27(16-17)18-4-2-1-3-5-18/h1-9,14-16H,10-13H2
UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 900n/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as potentiation of glutamate-induced calcium mobilization by F...


Bioorg Med Chem Lett 22: 3235-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.032
BindingDB Entry DOI: 10.7270/Q2QJ7J9Z
More data for this
Ligand-Target Pair