BDBM50381949 CHEMBL2023118

SMILES CCn1cc(NC(=O)Cc2ccc(Oc3ccnc4cc(OC)ccc34)cc2OC)cn1

InChI Key InChIKey=INFXGMKRYCEOFJ-UHFFFAOYSA-N

Data  4 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50381949   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

LigandBDBM50381949(CHEMBL2023118)Copy SMILESCopy InChI

Affinity DataIC50:  0.700nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

LigandBDBM50381949(CHEMBL2023118)Copy SMILESCopy InChI

Affinity DataIC50:  700nMAssay Description:Inhibition of Flt3More data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathway
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

LigandBDBM50381949(CHEMBL2023118)Copy SMILESCopy InChI

Affinity DataIC50:  67nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

LigandBDBM50381949(CHEMBL2023118)Copy SMILESCopy InChI

Affinity DataIC50:  5nMAssay Description:Inhibition of CSF-1RMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI