BDBM50382009 CHEMBL2023296

SMILES Cc1cn2c(cnc2c(Nc2cc(CN3CCCCC3)ns2)n1)-c1cnn(CC(=O)NCc2cccc(F)c2F)c1

InChI Key InChIKey=TTXUUHWJDGZPDA-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50382009   

TargetAurora kinase A(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50382009(CHEMBL2023296)
Affinity DataIC50:  45nMAssay Description:Inhibition of aurora A kinase using 5TAMRA-GRTGRRNSICOOH as substrate by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50382009(CHEMBL2023296)
Affinity DataEC50:  870nMAssay Description:Inhibition of aurora B kinase in human HCT116 cells assessed as inhibition of histone H3 phosphorylation incubated for 1 hr by Hoechst 33342 staining...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed