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BDBM50382229 CHEMBL2024657

SMILES: FC(F)(F)c1cc(NC(=O)Nc2cccc3cc[nH]c23)ccc1Cl

InChI Key: InChIKey=GXTDSKILHSBKND-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50382229   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM50382229
PNG
(CHEMBL2024657)
Show SMILES FC(F)(F)c1cc(NC(=O)Nc2cccc3cc[nH]c23)ccc1Cl
Show InChI InChI=1S/C16H11ClF3N3O/c17-12-5-4-10(8-11(12)16(18,19)20)22-15(24)23-13-3-1-2-9-6-7-21-14(9)13/h1-8,21H,(H2,22,23,24)
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 67n/an/an/an/an/an/a



Bayer Yakuhin, Ltd

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPV1 expressed in CHOluc9aeq cells assessed as inhibition of capsaicin-stimulated response by aequorin and CRE-lucifear...


Bioorg Med Chem Lett 22: 3408-11 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.108
BindingDB Entry DOI: 10.7270/Q2C24XF7
More data for this
Ligand-Target Pair