BDBM50382290 CARIPRAZINE HYDROCHLORIDE::RGH-188 HCL::US20240254109, Example Cariprazine

SMILES: CN(C)C(=O)NC1CCC(CC1)CCN2CCN(CC2)c3cccc(c3Cl)Cl

InChI Key: InChIKey=KPWSJANDNDDRMB-UHFFFAOYSA-N

Data: 3 KI  7 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50382290   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Human)	BDBM50382290 (RGH-188 HCL | CARIPRAZINE HYDROCHLORIDE | US202402...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.890	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Human)	BDBM50382290 (RGH-188 HCL | CARIPRAZINE HYDROCHLORIDE | US202402...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	191	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A) dopamine receptor (Rat)	BDBM50382290 (RGH-188 HCL | CARIPRAZINE HYDROCHLORIDE | US202402...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A) dopamine receptor (Human)	BDBM50382290 (RGH-188 HCL | CARIPRAZINE HYDROCHLORIDE | US202402...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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D(1B) dopamine receptor (Human)	BDBM50382290 (RGH-188 HCL | CARIPRAZINE HYDROCHLORIDE | US202402...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Rat)	BDBM50382290 (RGH-188 HCL | CARIPRAZINE HYDROCHLORIDE | US202402...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50382290 (RGH-188 HCL | CARIPRAZINE HYDROCHLORIDE | US202402...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50382290 (RGH-188 HCL | CARIPRAZINE HYDROCHLORIDE | US202402...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50382290 (RGH-188 HCL | CARIPRAZINE HYDROCHLORIDE | US202402...) Show SMILES Show InChI	GoogleScholar	UniChem		0.810	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50382290 (RGH-188 HCL | CARIPRAZINE HYDROCHLORIDE | US202402...) Show SMILES Show InChI	GoogleScholar	UniChem		5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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