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BDBM50382390 CHEMBL2022161

SMILES: FC(F)(F)c1cccc(NC(=O)NC2=NC(=O)CCN2)c1

InChI Key: InChIKey=HHWCFIJUESFSTC-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50382390   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50382390
PNG
(CHEMBL2022161)
Show SMILES FC(F)(F)c1cccc(NC(=O)NC2=NC(=O)CCN2)c1
Show InChI InChI=1S/C12H11F3N4O2/c13-12(14,15)7-2-1-3-8(6-7)17-11(21)19-10-16-5-4-9(20)18-10/h1-3,6H,4-5H2,(H3,16,17,18,19,20,21)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Antagonist activity at human mGluR5 expressed in CHO-K1 cells assessed as inhibition of glutamate-induced intracellular calcium mobilization


ACS Med Chem Lett 2: 882-884 (2011)


Article DOI: 10.1021/ml200162f
BindingDB Entry DOI: 10.7270/Q2XW4KT8
More data for this
Ligand-Target Pair