BDBM50382540 CHEMBL2022577

SMILES CCOCCOc1cc(C)c(c(C)c1)-c1cccc(COc2ccc3C(CC(O)=O)COc3c2)c1

InChI Key InChIKey=GWJDMRAKYPGSSI-UHFFFAOYSA-N

Data  4 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50382540   

TargetFree fatty acid receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50382540(CHEMBL2022577)
Affinity DataEC50:  28nMAssay Description:Agonist activity at human GR40 receptor expressed in CHO cells assessed as increase in intracellular calcium concentration after 90 secs by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50382540(CHEMBL2022577)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human GP40 receptor expressed in CHO cells assessed as increase in intracellular calcium level for 90 secs by FLIPR assay in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50382540(CHEMBL2022577)
Affinity DataKi:  32nMAssay Description:Displacement of 3-[4-({2',6'-dimethyl-6-[(4-[3H])-phenylmethoxy]biphenyl-3-yl}methoxy)phenyl]propanoic acid from human GPR40 expressed in CHO cells a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50382540(CHEMBL2022577)
Affinity DataKi:  32nMAssay Description:Displacement of 3-[4-({2',6'-dimethyl-6-[(4-[3H])-phenylmethoxy]biphenyl-3-yl}methoxy)phenyl] propanoic acid from human GPR40 receptor expressed in C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50382540(CHEMBL2022577)
Affinity DataKi:  200nMAssay Description:Displacement of 3-[4-({2',6'-dimethyl-6-[(4-[3H])-phenylmethoxy]biphenyl-3-yl}methoxy)phenyl] propanoic acid from rat GPR40 receptor expressed in CHO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50382540(CHEMBL2022577)
Affinity DataKi:  300nMAssay Description:Displacement of 3-[4-({2',6'-dimethyl-6-[(4-[3H])-phenylmethoxy]biphenyl-3-yl}methoxy)phenyl]propanoic acid from rat GPR40 expressed in CHO cells aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed